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Fourth, the comment letter rejected the “Good Practice Guidelines” because they contained only general, non-binding recommendations and were not applicable to all journal editors. This critique is misguided, as the guidelines are not designed to be prescriptive but rather to offer a framework to guide editors in formulating their journal’s own policies, as explained above. Moreover, the guidelines are not applicable to all journals. The only relevant and objective standard is the US Public Health Service’s Guidelines on Conflict of Interest [2]. Another issue is whether to adopt a comprehensive conflict of interest policy covering not just authors and editors, but also publishers, reviewers, funders, and other stakeholders. This is a more complex issue, as in some nations editors’ professional code of conduct, like that in the UK, mandates that editors declare conflicts and set their own policies and standards. But there should be no need to make this more comprehensive than an actual policy. And there is no reason to insist that all of these stakeholders must always adhere to a single, uniform rule. Editors should be able to determine when it is appropriate to reject an article due to authors’ conflicts and when it is appropriate to accept it. As explained above, there will be circumstances in which it is appropriate to recommend a manuscript be rejected solely because it contains an incomplete conflict of interest disclosure. Likewise, there will be circumstances in which it is appropriate to reject an article because the journal has a conflict of interest policy that was not observed. Finally, for certain kinds of conflict of interest that are very important in new drug and vaccine development, editors may need to decline to review a manuscript that contains one of those conflicts. But the issue is not whether to reject or accept a manuscript. The issue is whether the editors have all the information they need to make an informed decision to accept or reject the manuscript. Editors can and should reject a manuscript if they do not have the information they need to make an informed decision; they should not feel compelled to reject just because the information is not in the manuscript.
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